ASI PrimeLine™ Syringe Pumps

ASI PrimeLine™ Syringe Pumps: unrivalled flow precision for HPLC, UHPLC and LC-MS

The PrimeLine™ Syringe Pumps from Analytical Scientific Instruments (ASI) are developed for applications where flow precision at nanolitre level is critical. In independent engineering evaluations with flow precision as the primary metric, the ASI 576 scored best in class for low flow rates at pressures up to 9.000 psi. The measured flow variability was 0,23% RSD at 1,7 µL/min in IPA at 4 bar, and 0,43% RSD at 1,4 µL/min in water at 620 bar. Both competitors tested came out at an RSD of about 1,9% and 2,8% under comparable conditions.

Models

576 Series (HPLC) is the HPLC version of the PrimeLine™ and supports pressures up to 9.000 psi (620 bar). The pump has a stepper motor including drive and controller, nano check valves and a graphical user interface via USB connection. Available in Ultem, PEEK, Teflon or 316 stainless steel.

578 Series (UHPLC) is the UHPLC version and supports pressures up to 20.000 psi (1.380 bar). Same construction as the 576 Series, but suitable for the highest pressures in modern UHPLC and nano-LC applications.

576 Infusion Syringe Pump is a special version for mass spectrometry, designed for tuning target analytes, ion suppression tests and matrix addition. Via an integrated selector valve, the pump can inject sample or wash solvent into a post-column medium-pressure fluid system. Flow rate range: 0,50 to 150 µL/min, accuracy ±0,5%, reproducibility 0,1%, maximum pressure 800 psi (optional UHPLC up to 9.000 psi).

Nano check valve technology

One of the key distinguishing features of the PrimeLine™ pumps is the ASI nano check valve technology. It eliminates the need for expensive rotary switching valves used in conventional syringe pumps. Rotary valves wear and produce particles that contaminate the system. The ASI nano check valves have no rotating moving parts, produce no particles and do not need replacing due to wear. This lowers the total cost of ownership and increases the reliability of the instrument.

Dual syringe and gradient option

The PrimeLine™ 576 and 578 are available with a dual syringe configuration for HPLC and UHPLC gradient elution. This allows isocratic and gradient programmes to run without external mixing equipment.

OEM options

The PrimeLine™ pumps are fully available for OEM private label applications. The mechanical assemblies are available separately for integration into third-party instruments. Versions without an integrated drive/controller for the stepper motor, without check valves or with other customisable features are available on request. Communication via Modbus RTU over RS485 makes integration into OEM software environments easy.

Applications

PrimeLine™ Syringe Pumps are used in HPLC and UHPLC, LC-MS and nanospray MS, liquid metering in process analysis, sampling systems, sample preparation, infusion for mass spectrometry tuning and ion suppression tests.

Properties

• Ongeëvenaarde flowprecisie: bewezen best-in-class in onafhankelijke benchmark
• 576 Series: HPLC, max. 9.000 psi (620 bar)
• 578 Series: UHPLC, max. 20.000 psi (1.380 bar)
• Infusion Pump version: 0,50 to 150 µL/min for mass spectrometry
• Nano check valves: no rotating parts, no particle formation
• Stepper motor with integrated drive and controller
• Graphical user interface via USB (Windows)
• Modbus RTU, RS485 for OEM software integration
• Material option: Ultem, PEEK, Teflon or 316 stainless steel
• Wash seal option for buffers
• Dual syringe for gradient option
• Horizontal and vertical mounting possible
• OEM private label and mechanical assemblies available
• Operating temperature: 4 to 40 °C

Technical specifications