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Blogs on HPLC

From HPLC to UHPLC: which components need to change?
06 August 2026
From HPLC to UHPLC: which components need to change?

Switching to UHPLC requires more than a new column. Read which components in the flow path...

Reading time: 4 minutes
Replacing a detector lamp: when does your deuterium lamp need replacing?
06 August 2026
Replacing a detector lamp: when does your deuterium lamp need replacing?

In many labs, a deuterium lamp is replaced too late because the light output decreases gra...

Reading time: 4 minutes
Peak broadening in HPLC: causes, dead volume and the Van Deemter equation
06 August 2026
Peak broadening in HPLC: causes, dead volume and the Van Deemter equation

Peak broadening leads to lower peaks, poorer resolution and less sensitivity. Read where i...

Reading time: 5 minutes
Choosing an HPLC column: which stationary phase suits your analysis?
06 August 2026
Choosing an HPLC column: which stationary phase suits your analysis?

The column is the most important choice in your method development. Read how to choose the...

Reading time: 5 minutes
Detecting and preventing leakage in your HPLC system
04 August 2026
Detecting and preventing leakage in your HPLC system

Leakage in an HPLC system can almost always be traced back to a limited number of causes. ...

Reading time: 4 minutes
Leakage in your HPLC system: causes, detection and prevention
28 July 2026
Leakage in your HPLC system: causes, detection and prevention

Leakage is one of the most common faults in an HPLC system. Read where leaks come from, ho...

Reading time: 4 minutes
1/4-28, 10-32 or M6: which thread do you use for HPLC fittings?
28 July 2026
1/4-28, 10-32 or M6: which thread do you use for HPLC fittings?

Three thread formats are used in HPLC, GC and mass spectrometry: 10-32, 1/4-28 and M6. Rea...

Reading time: 4 minutes
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PTFE, FEP or PFA tubing: what is the difference and which should you choose?
28 July 2026
PTFE, FEP or PFA tubing: what is the difference and which should you choose?

PTFE, FEP and PFA are very similar, but the technical differences determine the success of...

Reading time: 4 minutes
HPLC degasser: why degassing is essential and the advantages of Biotech DEGASi for OEM manufacturers
29 May 2026
HPLC degasser: why degassing is essential and the advantages of Biotech DEGASi for OEM manufacturers

Without proper degassing of the mobile phase, a single gas bubble leads to unreliable resu...

Reading time: 8 minutes
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