When do you have the right HPLC pump?
An HPLC pump may look like a commodity. It is not. The flow precision of your pump directly determines the retention time reproducibility of your separation. Pulsation affects the baseline of your detector. A seal that wears quickly costs you downtime at the moment you can least afford it. And if you integrate a pump into an OEM instrument, the communication interface determines how simple or complex the software integration will be.
ASI has solved these problems from the ground up. The patented floating pump seal considerably extends seal life. The nano check valve technology eliminates rotating wear parts. The Modbus RTU interface over RS485 or USB makes OEM integration easy. And in independent benchmark tests, the ASI PrimeLine syringe pump scored best-in-class for flow precision, with a measured RSD of 0.23% at 1.7 µL/min and 620 bar.
ASI HPLC pumps
What application do you need a pump for?
Analytical HPLC and UHPLC For analytical separation from micro to semi-preparative scale, the ASI 540 Series is the obvious choice. Available with pump heads from Micro (0.5 µL/min) to Flash Prep (300 mL/min), in stainless steel or biocompatible PEEK, and as an isocratic model (541) or gradient system (540G). The integrated solvent compressibility compensation from a library of 14 solvents guarantees accurate flow delivery regardless of the solvent.
Nanolitre precision for LC-MS and UHPLC For applications where nanolitre-level flow precision is critical, the ASI PrimeLine syringe pump series offers unrivalled stability. The 576 Series supports pressures up to 9,000 psi, the 578 Series up to 20,000 psi. The ASI 576 Infusion Pump is specifically developed for mass spectrometry tuning, ion suppression tests and matrix addition at flow rates from 0.5 to 150 µL/min.
Preparative chromatography For prep LC at lab and pilot scale, the ASI 545 Star Prep Pump offers pulsation of max. 1% ΔP/P at flow rates from 0.1 mL/min to 1,500 mL/min and pressures up to 10,000 psi. Available in stainless steel, titanium and PEEK, with low-pressure and high-pressure gradient options.
Continuous process metering and pilot production For 24/7 production environments where robustness comes first, the ASI 546 Star Pilot Pump is the choice. Pulsation below 5% ΔP/P, flow ranges up to 1,500 mL/min, pressures up to 10,000 psi and up to 1,000 programmable method steps via Modbus.
Which ASI pump suits your application?
| Model | Type | Flowbereik | Max. pressure | Best choice for |
|---|
| 540 Series | HPLC/UHPLC reciprocerende pomp | 0,5 µL/min – 300 mL/min | 15.000 psi | Analytical HPLC, UHPLC, gradient elution, daily lab use |
| PrimeLine 576 | HPLC syringe pump | nL/min – µL/min | 9.000 psi | LC-MS, nanolitre precision, low flow, MS infusion |
| PrimeLine 578 | UHPLC syringe pump | nL/min – µL/min | 20.000 psi | UHPLC, nano-LC, highest flow precision at extremely high pressure |
| 545 Star Prep | Preparative metering pump | 0,1 – 1.500 mL/min | 10.000 psi | Prep chromatography, lowest pulsation, pilot scale |
| 546 Star Pilot | Proces meteringpomp | 2 – 1.500 mL/min | 10.000 psi | 24/7 production, HP liquid metering, process scale |
The three key questions for your choice
How low is your flow rate? For nanolitre to microlitre flows, the PrimeLine syringe pump series is the only choice. For flows from a few µL/min to hundreds of mL/min, the reciprocating models (540, 545, 546) are suitable.
How strict are your pulsation requirements? The 545 offers the lowest pulsation (1% ΔP/P) and is the choice for the most sensitive detectors. The 546 is designed more robustly for 24/7 use and reaches less than 5% ΔP/P. The 540 achieves 1% ΔP/P at 1,500 psi for analytical applications.
Is it a laboratory pump or an OEM module? All models are available for OEM integration. The PrimeLine series and the 545/546 are also available as a separate mechanical assembly without housing, suitable for direct integration into an instrument chassis.
OEM integration: what makes ASI different
ASI has supplied OEM pump assemblies for proteomics and LC-MS, process instrumentation, pharmaceutical production, supercritical fluid chromatography, preparative chromatography, biotech and SEC/GPC systems. The pumps are available as a separate pump module, as a pump module including hydraulic module and controller on a base plate, or as a fully configured assembly with wash pump, damper and servo controller.
All models support Modbus RTU over RS485 or USB for integration into OEM software environments. Private label is available as standard, for small and large volumes. Custom configurations to specification are the norm, not the exception.
Why ASI via Inacom?
Inacom Instruments is the ASI distributor for the Benelux. You benefit from local technical support, fast quotations and a direct line to the manufacturer for OEM specification questions. Whether you are looking for a single laboratory pump or a pump module for series instrument production, we help you select the right configuration.